Advancements in leukemia management: Bridging diagnosis, prognosis and nanotechnology (Review)
- Authors:
- Jingbo Li
- Yingxue Wang
- Chunli Dong
- Lifu Luo
-
Affiliations: Department of Ultrasound Medicine, The Second Hospital of Jilin University, Changchun, Jilin 130000, P.R. China, Department of Critical Care Medicine, Jilin People's Hospital, Changchun, Jilin 130021, P.R. China, Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin 130000, P.R. China - Published online on: October 2, 2024 https://doi.org/10.3892/ijo.2024.5700
- Article Number: 112
-
Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
Bose P and Bandyopadhyay S: A comprehensive assessment and classification of acute lymphocytic leukemia. Math Comput Appl. 29:452024. | |
Sekeres MA, Guyatt G, Abel G, Alibhai S, Altman JK, Buckstein R, Choe H, Desai P, Erba H, Hourigan CS, et al: American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults. Blood Adv. 4:3528–3549. 2020. View Article : Google Scholar : PubMed/NCBI | |
Tirado HA, Balasundaram N, Laaouimir L, Erdem A and van Gastel N: Metabolic crosstalk between stromal and malignant cells in the bone marrow niche. Bone Rep. 18:1016692023. View Article : Google Scholar : PubMed/NCBI | |
Kaszuba CM, Rodems BJ, Sharma S, Franco EI, Ashton JM, Calvi LM and Bajaj J: Identifying bone marrow microenvironmental populations in myelodysplastic Syndrome and acute myeloid leukemia. J Vis Exp. Nov 10–2023.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
Ye B, Sheng Y, Zhang M, Hu Y and Huang H: Early detection and intervention of clonal hematopoiesis for preventing hematological malignancies. Cancer Lett. 538:2156912022. View Article : Google Scholar : PubMed/NCBI | |
Coombs CC, Zehir A, Devlin S, Zehir A, Devlin S, Kishtagari A, Hyman DM, Solit D, Robson M, Baselga J, et al: Mutational analysis of clonal hematopoiesis in solid tumor patients Illustrates the critical role of systemic anti-cancer therapies in the evolution of somatic leukemia disease alleles. Blood. 128:372016. View Article : Google Scholar | |
Stengel A, Baer C, Walter W, Meggendorfer M, Kern W, Haferlach T and Haferlach C: Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies. Blood Adv. 5:4426–4434. 2021. View Article : Google Scholar : PubMed/NCBI | |
Shiozawa Y, Havens AM, Pienta KJ and Taichman RS: The bone marrow niche: Habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites. Leukemia. 22:941–950. 2008. View Article : Google Scholar : PubMed/NCBI | |
Chowdhury MM: Stem cell in cancer disease cure vs cause. 2022, https://dspace.bracu.ac.bd/xmlui/bitstream/handle/10361/17759/18146041_PHR.pdf?sequence=1. | |
Hoffman R: Progress in the development of systems for in vitro expansion of human hematopoietic stem cells. Curr Opin Hematol. 6:184–191. 1999. View Article : Google Scholar : PubMed/NCBI | |
Landau DA, Carter SL, Getz G and Wu CJ: Clonal evolution in hematological malignancies and therapeutic implications. Leukemia. 28:34–43. 2014. View Article : Google Scholar | |
Wang X, Huang S and Chen JL: Understanding of leukemic stem cells and their clinical implications. Mol Cancer. 16:22017. View Article : Google Scholar : PubMed/NCBI | |
Komarova NL, Burger JA and Wodarz D: Evolution of ibrutinib resistance in chronic lymphocytic leukemia (CLL). Proc Natl Acad Sci USA. 111:13906–13911. 2014. View Article : Google Scholar : PubMed/NCBI | |
Shimony S, Stahl M and Stone RM: Acute myeloid leukemia: 2023 update on diagnosis, risk-stratification, and management. Am J Hematol. 98:502–526. 2023. View Article : Google Scholar : PubMed/NCBI | |
Jabbour E and Kantarjian H: Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring. Am J Hematol. 93:442–459. 2018. View Article : Google Scholar : PubMed/NCBI | |
Miranda-Filho A, Piñeros M, Ferlay J, Soerjomataram I, Monnereau A and Bray F: Epidemiological patterns of leukaemia in 184 countries: A population-based study. Lancet Haematol. 5:e14–e24. 2018. View Article : Google Scholar : PubMed/NCBI | |
Lin K, Jia H, Cao M, Xu T, Chen Z, Song X, Miao Y, Yao T, Dong C, Shao J, et al: Epidemiological characteristics of leukemia in China, 2005-2017: A log-linear regression and age-period-cohort analysis. BMC Public Health. 23:16472023. View Article : Google Scholar : PubMed/NCBI | |
Zeidan AM, Mahmoud D, Kucmin-Bemelmans IT, Alleman CJ, Hensen M, Skikne B and Smith BD: Economic burden associated with acute myeloid leukemia treatment. Expert Rev Hematol. 9:79–89. 2016. View Article : Google Scholar | |
Arber DA, Campo E and Jaffe ES: Advances in the classification of myeloid and lymphoid neoplasms. Virchows Arch. 482:1–9. 2023. View Article : Google Scholar : PubMed/NCBI | |
Al-Bayati A, Al-Bayti A and Husain V: A short review about chronic myeloid leukemia. J Life Bio Sci Res. 4:15–19. 2023. View Article : Google Scholar | |
Sell S: Leukemia: Stem cells, maturation arrest, and differentiation therapy. Stem Cell Rev. 1:197–206. 2005. View Article : Google Scholar | |
Cheng Y, Luo H and Kharas MG: Rubbing out leukemia stem cells by erasing the eraser. Cell Stem Cell. 27:3–5. 2020. View Article : Google Scholar : PubMed/NCBI | |
Kassahun W, Tesfaye G, Bimerew LG, Fufa D, Adissu W and Yemane T: Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study. Adv Hematol. 2020:1–7. 2020. View Article : Google Scholar | |
Jahic A, Iljazovic E, Hasic S, Arnautovic AC, Sabitovic D, Mesanovic S, Sahovic H and Simendic V: Prognostic Parameters of Acute Myeloid Leukaemia at Presentation. Med Arch. 71:20–24. 2017. View Article : Google Scholar : PubMed/NCBI | |
Zhang H, Luo XQ, Zhang P, Huang LB, Zheng YS, Wu J, Zhou H, Qu LH, Xu L and Chen YQ: MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia. PLoS One. 4:e78262009. View Article : Google Scholar : PubMed/NCBI | |
Kardum-Skelin I, Planinc-Peraica A, Ostojić Kolonić S, Radić-Kristo D, Milas M, Vrhovac R, Sustercić D, Minigo H and Jaksić B: Clinical and laboratory prognostic parameters for leukemic types of chronic lymphoproliferative diseases. Acta Med Croatica. 62:351–364. 2008.In Croatian. | |
Othieno-Abinya NA, Mwanda WO, Maina MD, Odhiambo AO, Mwanzi SA and Oyiro PO: Haematological parameters in chronic myeloid leukaemia as determinants of clinical manifestations in this disease. J Clin Oncol. 34:e185292016. View Article : Google Scholar | |
Spiers AS: Management of the chronic leukemias: Special considerations in the elderly patient. part II: Chronic granulocytic leukemia. Hematology. 6:357–380. 2001. View Article : Google Scholar : PubMed/NCBI | |
Sharma K, Puniyani RR, Bhat SV, Advani SH, Hegde U and Rao S: Blood viscosity parameter correlation with types of leukemia. Physiol Chem Phys Med NMR. 24:159–164. 1992.PubMed/NCBI | |
Germing U, Strupp C, Aivado M and Gattermann N: New prognostic parameters for chronic myelomonocytic leukemia? Blood. 100:731–732; author reply 732-3. 2002. View Article : Google Scholar | |
Tonorezos ES, Robien K, Eshelman-Kent D, Moskowitz CS, Church TS, Ross R and Oeffinger KC: Contribution of diet and physical activity to metabolic parameters among survivors of childhood leukemia. Cancer Causes Control. 24:313–321. 2013. View Article : Google Scholar : | |
Haferlach C, Dicker F, Weiss T, Schnittger S, Beck C, Grote-Metke A, Oruzio D, Kern W and Haferlach T: Toward a comprehensive prognostic scoring system in chronic lymphocytic leukemia based on a combination of genetic parameters. Genes Chromosomes Cancer. 49:851–859. 2010. View Article : Google Scholar : PubMed/NCBI | |
Jaeger BA, Tauer JT, Ulmer A, Kuhlisch E, Roth HJ and Suttorp M: Changes in bone metabolic parameters in children with chronic myeloid leukemia on imatinib treatment. Med Sci Monit. 18:CR721–CR728. 2012. View Article : Google Scholar : PubMed/NCBI | |
Letestu R, Lévy V, Eclache V, Baran-Marszak F, Vaur D, Naguib D, Schischmanoff O, Katsahian S, Nguyen-Khac F, Davi F, et al: Prognosis of Binet stage A chronic lymphocytic leukemia patients: the strength of routine parameters. Blood. 116:4588–4590. 2010. View Article : Google Scholar : PubMed/NCBI | |
Negrini M, Cutrona G, Bassi C, Fabris S, Zagatti B, Colombo M, Ferracin M, D'Abundo L, Saccenti E, Matis S, et al: microRNA ome expression in chronic lymphocytic leukemia: Comparison with Normal B-cell subsets and correlations with prognostic and clinical parameters. Clin Cancer Res. 20:4141–4153. 2014. View Article : Google Scholar : PubMed/NCBI | |
Rigolin GM, Cibien F, Martinelli S, Formigaro L, Rizzotto L, Tammiso E, Saccenti E, Bardi A, Cavazzini F, Ciccone M, et al: Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia with 'normal' FISH: Correlations with clinicobiologic parameters. Blood. 119:2310–2313. 2012. View Article : Google Scholar : PubMed/NCBI | |
Babusikova O, Stevulova L and Fajtova M: Immunophenotyping parameters as prognostic factors in T-acute leukemia patients. Neoplasma. 56:508–513. 2009. View Article : Google Scholar : PubMed/NCBI | |
Joncourt F, Oberlischraummli AE, Stadler M, Buser K, Franscini L, Fey MF and Cerny T: Patterns of Drug Resistance Parameters in Adult Leukemia. Leuk Lymphoma. 17:101–109. 1995. View Article : Google Scholar : PubMed/NCBI | |
Baumgartner A, Zueger N, Bargetzi A, Medinger M, Passweg JR, Stanga Z, Mueller B, Bargetzi M and Schuetz P: Association of nutritional parameters with clinical outcomes in patients with acute myeloid leukemia undergoing haematopoietic stem cell transplantation. Ann Nutr Metab. 69:89–98. 2016. View Article : Google Scholar : PubMed/NCBI | |
Sillaber C, Mayerhofer M, Agis H, Sagaster V, Mannhalter C, Sperr WR, Geissler K and Valent P: Chronic myeloid leukemia: Pathophysiology, diagnostic parameters, and current treatment concepts. Wien Klin Wochenschr. 115:485–504. 2003. View Article : Google Scholar : PubMed/NCBI | |
Zittoun R, Cadiou M, Bayle C, Suciu S, Solbu G and Hayat M: Prognostic value of cytologic parameters in acute myelogenous leukemia. Cancer. 53:1526–1532. 1984. View Article : Google Scholar : PubMed/NCBI | |
Piard C, Bressolle F, Fakhoury M, Zhang D, Yacouben K, Rieutord A and Jacqz-Aigrain E: A limited sampling strategy to estimate individual pharmacokinetic parameters of methotrexate in children with acute lymphoblastic leukemia. Cancer Chemother Pharmacol. 60:609–620. 2006. View Article : Google Scholar | |
Halonen P, Mattila J, Suominen P, Ruuska T, Salo MK and Mäkipernaa A: Iron overload in children who are treated for acute lymphoblastic leukemia estimated by liver siderosis and serum iron parameters. Pediatrics. 111:91–96. 2003. View Article : Google Scholar : PubMed/NCBI | |
Prabhu M, Kochupillai V, Sharma S, Ramachandran P, Sundaram KR, Bijlani L and Ahuja RK: Prognostic assessment of various parameters in chronic myeloid leukemia. Cancer. 58:1357–1360. 1986. View Article : Google Scholar : PubMed/NCBI | |
Shinawi T, Hill V, Dagklis A, Baliakas P, Stamatopoulos K, Agathanggelou A, Stankovic T, Maher ER, Ghia P and Latif F: KIBRAgene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia. Epigenetics. 7:211–215. 2012. View Article : Google Scholar : PubMed/NCBI | |
Royer-Pokora B, Beug H, Claviez M, Winkhardt HJ, Friis RR and Graf T: Transformation parameters in chicken fibroblasts transformed by AEV and MC29 avian leukemia viruses. Cell. 13:751–760. 1978. View Article : Google Scholar : PubMed/NCBI | |
Oliveira GB, Pereira FG, Metze K and Lorand-Metze I: Spontaneous apoptosis in chronic lymphocytic leukemia and its relationship to clinical and cell kinetic parameters. Cytometry. 46:329–335. 2001. View Article : Google Scholar : PubMed/NCBI | |
Hofmann-Lehmann R, Holznagel E, Ossent P and Lutz H: Parameters of disease progression in long-term experimental feline retrovirus (feline immunodeficiency virus and feline leukemia virus) infections: hematology, clinical chemistry, and lymphocyte subsets. Clin Diagn Lab Immunol. 4:33–42. 1997. View Article : Google Scholar : PubMed/NCBI | |
Chiaretti S, Marinelli M, Del Giudice I, Bonina S, Piciocchi A, Messina M, Vignetti M, Rossi D, Di Maio V, Mauro FR, et al: NOTCH1, SF3B1, BIRC3andTP53mutations in patients with chronic lymphocytic leukemia undergoing first-line treatment: correlation with biological parameters and response to treatment. Leuk Lymphoma. 55:2785–2792. 2014. View Article : Google Scholar : PubMed/NCBI | |
Li J, Zheng R, Niu J, Song X, Wu W, Fan R and Gong T: Correlation of intravoxel incoherent motion parameters and histological characteristics from infiltrated marrow in patients with acute leukemia. J Magn Reson Imaging. 51:1720–1726. 2019. View Article : Google Scholar : PubMed/NCBI | |
Dhasmana R, Prakash A, Gupta N and Verma SK: Ocular manifestations in leukemia and myeloproliferative disorders and their association with hematological parameters. Ann Afr Med. 15:97–103. 2016. View Article : Google Scholar : PubMed/NCBI | |
Omer SH, AA K, IM O, OH M, HN A and Elamin BK: Prevalence of the different FAB sub type of Acute Myeloid Leukemia related to hematological parameters in Sudanese. J Hematol Blood Disord. 3:1022017. View Article : Google Scholar | |
Heintel D, Schwarzinger I, Chizzali-Bonfadin C, Thalhammer R, Schwarzmeier J, Fritzer-Szekeres M, Weltermann A, Simonitsch I, Lechner K and Jaeger U: Association of CD38 antigen expression with other prognostic parameters in early stages of chronic lymphocytic leukemia. Leuk Lymphoma. 42:1315–1321. 2001. View Article : Google Scholar | |
Molica S, Cutrona G, Vitelli G, Mirabelli R, Molica M, Digiesi G, Ribatti D, Ferrarini M and Vacca A: Markers of increased angiogenesis and their correlation with biological parameters identifying high-risk patients in early B-cell chronic lymphocytic leukemia. Leuk Res. 31:1575–1578. 2007. View Article : Google Scholar : PubMed/NCBI | |
Levine PH, Merrill DA, Bethlenfalvay NC, Dabich L, Stevens DA and Waggoner DE: A longitudinal comparison of antibodies to epstein-barr virus and clinical parameters in chronic lymphocytic leukemia and chronic myelocytic leukemia. Blood. 38:479–484. 1971. View Article : Google Scholar : PubMed/NCBI | |
Martell RE, Peterson BL, Cohen HJ, Petros WP, Rai KR, Morrison VA, Elias L, Shepherd L, Hines J, Larson RA, et al: Analysis of age, estimated creatinine clearance and pretreatment hematologic parameters as predictors of fludarabine toxicity in patients treated for chronic lymphocytic leukemia: A CALGB (9011) coordinated intergroup study. Cancer Chemother Pharmacol. 50:37–45. 2002. View Article : Google Scholar : PubMed/NCBI | |
Bergmann MA, Eichhorst BF, Busch R, Adorf D, Stilgenbauer S, Eckart MJ, Wendtner CM and Hallek M; GCLLSG: Prospective Evaluation of Prognostic Parameters in Early Stage Chronic Lymphocytic Leukemia (CLL): Results of the CLL1-Protocol of the German CLL Study Group (GCLLSG). Blood. 110:6252007. View Article : Google Scholar | |
Sinisalo M, Aittoniemi J, Koski T, Tobin G, Thunberg U, Sundström C, Rosenquist R, Käyhty H and Vilpo J: Similar Humoral Immunity Parameters in Chronic Lymphocytic Leukemia Patients Independent of VH Gene Mutation Status. Leuk Lymphoma. 45:2451–2454. 2004. View Article : Google Scholar : PubMed/NCBI | |
Browman G, Goldberg J, Gottlieb AJ, Preisler HD, Azarnia N, Priore RL, Brennan JK, Vogler WR, Winton EF, Miller KB, et al: The clonogenic assay as a reproducible in vitro system to study predictive parameters of treatment outcome in acute nonlymphoblastic leukemia. Am J Hematol. 15:227–235. 1983. View Article : Google Scholar : PubMed/NCBI | |
Wieser R, Scheideler M, Hackl H, Engelmann M, Schneckenleithner C, Hiden K, Papak C, Trajanoski Z, Sill H and Fonatsch C: microRNAs in acute myeloid leukemia: Expression patterns, correlations with genetic and clinical parameters, and prognostic significance. Genes Chromosomes Cancer. 49:193–203. 2010. View Article : Google Scholar | |
Valet G, Repp R, Link H, Ehninger A and Gramatzki MM; SHG-AML study group: Pretherapeutic identification of high-risk acute myeloid leukemia (AML) patients from immunophenotypic, cytogenetic, and clinical parameters. Cytometry B Clin Cytom. 53:4–10. 2003. View Article : Google Scholar : PubMed/NCBI | |
Valent P, Agis H, Sperr W, Sillaber C and Horny HP: Diagnostic and prognostic value of new biochemical and immunohistochemical parameters in chronic myeloid leukemia. Leuk Lymphoma. 49:635–638. 2008. View Article : Google Scholar : PubMed/NCBI | |
Zimm S, Reaman G, Murphy RF and Poplack DG: Biochemical parameters of mercaptopurine activity in patients with acute lymphoblastic leukemia. Cancer Res. 46:1495–1498. 1986.PubMed/NCBI | |
Yang JH, Kim Y, Lim J, Kim M, Oh EJ, Lee HK, Park YJ, Min WS, Cho B, Lee K and Han K: Determination of acute leukemia lineage with new morphologic parameters available in the complete blood cell count. Ann Clin Lab Sci. 44:19–26. 2014.PubMed/NCBI | |
Olson KC, Moosic KB, Jones MK, Larkin PMK, Olson TL, Toro MF, Fox TE, Feith DJ and Loughran TP Jr: Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations. Cancer Med. 9:6533–6549. 2020. View Article : Google Scholar : PubMed/NCBI | |
Srinivasan S, Cui H, Gao Z, Liu M, Lu S, Mkandawire W, Narykov O, Sun M and Korkin D: Structural Genomics of SARS-CoV-2 indicates evolutionary conserved functional regions of viral proteins. Viruses. 12:3602020. View Article : Google Scholar : PubMed/NCBI | |
Hallek M: Chronic lymphocytic leukemia: 2020 update on diagnosis, risk stratification and treatment. Am J Hematol. 94:1266–1287. 2019. View Article : Google Scholar : PubMed/NCBI | |
Feller N, van der Pol MA, van Stijn A, Weijers GW, Westra AH, Evertse BW, Ossenkoppele GJ and Schuurhuis GJ: MRD parameters using immunophenotypic detection methods are highly reliable in predicting survival in acute myeloid leukaemia. Leukemia. 18:1380–1390. 2004. View Article : Google Scholar : PubMed/NCBI | |
Mohammadi Kanesbi M, Jarahi L and Keramati MR: Blood parameters in treatment with arsenic trioxide in acute promyelocytic leukemia: A systematic review. Int J Hematol Oncol Stem Cell Res. 14:130–139. 2020.PubMed/NCBI | |
Al-Bayaa IM, Al-Rubaie HA and Al-Shammari HH: Evaluation of hepatocyte growth factor in iraqi patients with acute myeloid leukemia: Its correlation with clinical parameters and response to induction therapy. Open Access Maced J Med Sci. 8:49–53. 2020. View Article : Google Scholar | |
Khazaal MS, Hamdan FB and Al-Mayah QS: Association of BCR/ABL transcript variants with different blood parameters and demographic features in Iraqi chronic myeloid leukemia patients. Mol Genet Genomic Med. 7:e8092019. View Article : Google Scholar : PubMed/NCBI | |
Ogasawara A, Matsushita H, Tanaka Y, Shirasugi Y, Ando K, Asai S and Miyachi H: A simple screening method for the diagnosis of chronic myeloid leukemia using the parameters of a complete blood count and differentials. Clin Chim Acta. 489:249–253. 2019. View Article : Google Scholar | |
Michailov Y, Lunenfeld E, Kapilushnik J, Friedler S, Meese E and Huleihel M: Acute myeloid leukemia affects mouse sperm parameters, spontaneous acrosome reaction, and fertility capacity. Int J Mol Sci. 20:2192019. View Article : Google Scholar : PubMed/NCBI | |
Virk H, Varma N, Naseem S, Bihana I and Sukhachev D: Utility of cell population data (VCS parameters) as a rapid screening tool for Acute Myeloid Leukemia (AML) in resource-constrained laboratories. J Clin Lab Anal. 33:e226792019. View Article : Google Scholar | |
Vigón L, Luna A, Galán M, Rodríguez-Mora S, Fuertes D, Mateos E, Piris-Villaespesa M, Bautista G, San José E, Rivera-Torres J, et al: Identification of immunological parameters as predictive biomarkers of relapse in patients with chronic myeloid leukemia on treatment-free remission. J Clin Med. 10:422020. View Article : Google Scholar : PubMed/NCBI | |
Mahmood R, Khan SA, Altaf C, Malik HS and Khadim MT: Clinicohematological parameters and outcomes in a cohort of chronic lymphocytic leukemia patients with Deletion 17p from Pakistan. Blood Res. 53:276–280. 2018. View Article : Google Scholar : PubMed/NCBI | |
Kim H, Ahn SI, Jhoo JW and Kim GY: Comparison of Allergic Parameters between Whey Protein Concentrate and Its Hydrolysate in Rat Basophilic Leukemia (RBL)-2H3 Cells. Korean J Food Sci Anim Resour. 38:780–793. 2018.PubMed/NCBI | |
Schillinger F, Sourdeau E, Boubaya M, Baseggio L, Clauser S, Cornet E, Debord C, Defour JP, Dubois F, Eveillard M, et al: A new approach for diagnosing chronic myelomonocytic leukemia using structural parameters of Sysmex XN™ analyzers in routine laboratory practice. Scand J Clin Lab Invest. 78:159–164. 2018. View Article : Google Scholar : PubMed/NCBI | |
Khan MI: Acute Myeloid Leukemia: Pattern of clinical and hematological parameters in a tertiary care centre. Int J Pathol. 11:58–63. 2018. | |
Podszywalow-Bartnicka P, Kominek A, Wolczyk M, Kolba MD, Swatler J and Piwocka K: Characteristics of live parameters of the HS-5 human bone marrow stromal cell line cocultured with the leukemia cells in hypoxia, for the studies of leukemia-stroma cross-talk. Cytometry A. 93:929–940. 2018. View Article : Google Scholar : PubMed/NCBI | |
Nägele V, Kratzer A, Zugmaier G, Holland C, Hijazi Y, Topp MS, Gökbuget N, Baeuerle PA, Kufer P, Wolf A and Klinger M: Changes in clinical laboratory parameters and pharmacodynamic markers in response to blinatumomab treatment of patients with relapsed/refractory ALL. Exp Hematol Oncol. 6:142017. View Article : Google Scholar : PubMed/NCBI | |
Lekovic D, Gotic M, Milic N, Zivojinovic B, Jovanovic J, Colovic N, Milosevic V and Bogdanovic A: Predictive parameters for imatinib failure in patients with chronic myeloid leukemia. Hematology. 22:460–466. 2017.PubMed/NCBI | |
Burhan I: Estimation Of Alpha-Fetoprotein (AFP) and some of biochemical parameters in leukemia patients. World J Pharm Pharma Sci. 5:2275–2283. 2017. | |
Elzubeir MA, Angi A, Rahoum H, Ismail IA, Mohammed ME, Yousef MM, Khair SM, Namarq Alaaldeen SA, Osman RAM, Duaa Ali AA, et al: Prognostic Significance of Immune Function Parameters (CD4, CD8 and CD4/CD8 ratio) in Sudanese Patients with Chronic Lymphocytic leukemia. Int J Multidiscip Curr Res. 4:7650–653. 2016. | |
Wenn K, Tomala L, Wilop S, Vankann L, Hasenbank C, Frank O, Hochhaus A, Giles FJ, Lange T, Müller MC, et al: Telomere length at diagnosis of chronic phase chronic myeloid leukemia (CML-CP) identifies a subgroup with favourable prognostic parameters and molecular response according to the ELN criteria after 12 months of treatment with nilotinib. Leukemia. 29:2402–2404. 2015. View Article : Google Scholar : PubMed/NCBI | |
Trendowski M, Wong V, Zoino JN, Christen TD, Gadeberg L, Sansky M and Fondy TP: Preferential enlargement of leukemia cells using cytoskeletal-directed agents and cell cycle growth control parameters to induce sensitivity to low frequency ultrasound. Cancer Lett. 360:160–170. 2015. View Article : Google Scholar : PubMed/NCBI | |
Huang Z, Liu WJ, Guo QL and Liu CY: Platelet parameters and expression of platelet membrane glycoprotein in childhood acute lymphoblastic leukemia. Genet Mol Res. 14:16074–16089. 2015. View Article : Google Scholar : PubMed/NCBI | |
Rabizadeh E, Pickholtz I, Barak M, Isakov E, Zimra Y and Froom P: Acute leukemia detection rate by automated blood count parameters and peripheral smear review. Int J Lab Hematol. 37:44–49. 2014. View Article : Google Scholar : PubMed/NCBI | |
Koltan S, Debski R, Koltan A, Grzesk E, Tejza B, Eljaszewicz A, Gackowska L, Kubicka M, Kolodziej B, Kurylo-Rafinska B, et al: Phenotype of NK cells determined on the basis of selected immunological parameters in children treated due to acute lymphoblastic leukemia. Medicine (Baltimore). 94:e23692015. View Article : Google Scholar : PubMed/NCBI | |
Aljamaan K, Aljumah TK, Aloraibi S, Absar M and Iqbal Z: Low Frequency of ETV6-RUNX1 (t 12; 21) in Saudi Arabian pediatric acute lymphoblastic leukemia patients: Association with clinical parameters and early remission. Asian Pac J Cancer Prev. 16:7523–7527. 2015. View Article : Google Scholar : PubMed/NCBI | |
Rafiq N, Iqbal T, Shahid M and Muhammad F: Hematological and Biochemical Parameters in Pakistani Chronic Lymphoblastic Leukemia Patients. Pak J Life Soc Sci. 12:16–19. 2014. | |
Pietras W, Chaber R, Pela H, Trybucka K and Chybicka A: The recovery of immune system parameters in children following lymphoblastic leukemia therapy-preliminary report. Adv Clin Exp Med. 23:97–102. 2014. View Article : Google Scholar : PubMed/NCBI | |
Deschler B, Ihorst G, Platzbecker U, Germing U, März E, de Figuerido M, Fritzsche K, Haas P, Salih HR, Giagounidis A, et al: Parameters detected by geriatric and quality of life assessment in 195 older patients with myelodysplastic syndromes and acute myeloid leukemia are highly predictive for outcome. Haematologica. 98:208–216. 2013. View Article : Google Scholar : | |
Mauro MJ, Cortes JE, Kim DW, Pinilla-Ibarz J, Coutre PI, Paquette R, Chuah C, Nicolini FE, Apperley J, Khoury HJ, et al: Multivariate Analyses of the Clinical and Molecular Parameters Associated with Efficacy and Safety in Patients with Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Treated with Ponatinib in the PACE Trial. Blood. 120:37472012. View Article : Google Scholar | |
Dong HJ, Miao KR, Qiao C, Zhuang Y, Shen WY, Hong M, Fan L, Liu P, Xu W and Li JY: Polymorphisms and haplotypes in multidrug resistance 1 gene are not associated with chronic lymphocytic leukemia susceptibility and prognostic parameters of chronic lymphocytic leukemia in Chinese population. Leuk Lymphoma. 52:1003–1009. 2011. View Article : Google Scholar : PubMed/NCBI | |
Onida F, Kantarjian HM, Smith TL, Ball G, Keating MJ, Estey EH, Glassman AB, Albitar M, Kwari MI and Beran M: Prognostic factors and scoring systems in chronic myelomonocytic leukemia: A retrospective analysis of 213 patients. Blood. 99:840–849. 2002. View Article : Google Scholar : PubMed/NCBI | |
Sagatys EM and Zhang L: Clinical and laboratory prognostic indicators in chronic lymphocytic leukemia. Cancer Control. 19:18–25. 2012. View Article : Google Scholar | |
Jinlong S, Lin F, Yonghui L, Li Y and Weidong W: Identification of let-7a-2-3p or/and miR-188-5p as prognostic biomarkers in cytogenetically normal acute myeloid leukemia. PLoS One. 10:e01180992015. View Article : Google Scholar : PubMed/NCBI | |
Marcucci G, Mrózek K, Radmacher MD, Garzon R and Bloomfield CD: The prognostic and functional role of microRNAs in acute myeloid leukemia. Blood. 117:1121–1129. 2011. View Article : Google Scholar : | |
Labib HA, Elantouny NG, Ibrahim NF and Alnagar AA: Upregulation of microRNA-21 is a poor prognostic marker in patients with childhood B cell acute lymphoblastic leukemia. Hematology. 22:392–397. 2017. View Article : Google Scholar : PubMed/NCBI | |
Neaga A, Bagacean C, Tempescul A, Jimbu L, Mesaros O, Blag C, Tomuleasa C, Bocsan C, Gaman M and Zdrenghea M: MicroRNAs associated with a good prognosis of acute myeloid leukemia and their effect on macrophage polarization. Front Immunol. 11:5829152021. View Article : Google Scholar : PubMed/NCBI | |
Ciesielska M, Orzechowska B, Gamian A and Kazanowska B: Epidemiology of childhood acute leukemias. Postep Hig Med Dosw. 78:22–36. 2024.In Polish. View Article : Google Scholar | |
Mari JF, de Miranda ÉJFP, Mendes-Correa MC, Chow FC and Vidal JE: Progressive multifocal leukoencephalopathy and spectrum of predisposing conditions: A 20-year retrospective cohort study in a tertiary center in São Paulo, Brazil. Neurol Sci. Jul 15–2024.Epub ahead of print. View Article : Google Scholar | |
Aureli A, Marziani B, Venditti A, Sconocchia T and Sconocchia G: Acute Lymphoblastic Leukemia Immunotherapy Treatment: Now, Next, and Beyond. Cancers (Basel). 15:33462023. View Article : Google Scholar : PubMed/NCBI | |
Giannakaki AG, Giannakaki MN, Oikonomou E, Nikolettos K, Bothou A, Kotanidou S, Andreou S, Kritsotaki N, Nalmpanti T, Spanoudakis E, et al: Leukemia in pregnancy: Diagnosis and therapeutic approach (Review). Mol Clin Oncol. 21:792024. View Article : Google Scholar : PubMed/NCBI | |
van der Straten L, Levin MD, Dinnessen MAW, Visser O, Posthuma EFM, Doorduijn JK, Langerak AW, Kater AP and Dinmohamed AG: Risk of second primary malignancies in patients with chronic lymphocytic leukemia: A population-based study in the Netherlands, 1989-2019. Blood Cancer J. 13:152023. View Article : Google Scholar : PubMed/NCBI | |
Jain M, Rai A, Kushwaha R, Yadav G, Mishra S, Verma SP, Singh US, Tripathi AK and Kumar A: A cross sectional study on T Cells and Subsets in Chronic Lymphocytic Leukemia and their Association with Clinical Phenotype. Indian J Hematol Blood Transfus. 37:563–568. 2021. View Article : Google Scholar : PubMed/NCBI | |
Qurat Ul Ain, Akbar S, Gull S, Hussain M and Ayesha N: Leukemia detection using machine and deep learning through microscopic images-A review. Studies in Big Data. Jul 7–2022.Epub ahead of print. | |
Alcazer V, Le Meur G, Roccon M, Barriere S, Le Calvez B, Badaoui B, Spaeth A, Kosmider O, Freynet N, Eveillard M, et al: Evaluation of a machine-learning model based on laboratory parameters for the prediction of acute leukaemia subtypes: A multicentre model development and validation study in France. Lancet Digit Health. 6:e323–e333. 2024. View Article : Google Scholar : PubMed/NCBI | |
Vineela M, Reddy GDS, Karthik G, Muthukumaran N and Al Deen SH: Classification of Leukemia White Blood Cell Cancer. In: 2024 International Conference on Inventive Computation Technologies (ICICT); pp. 1233–1236. 2024 | |
Papadakis S, Liapis I, Papadhimitriou SI, Spanoudakis E, Kotsianidis I and Liapis K: Approach to acute myeloid leukemia with increased eosinophils and basophils. J Clin Med. 13:8762024. View Article : Google Scholar : PubMed/NCBI | |
Ahmed MR and Anis M: In vitro regeneration and the antioxidant enzymatic system on acclimatization of micropropagated Vitex trifolia L. Agroforest Syst. 88:437–447. 2014. View Article : Google Scholar | |
Li H, Xu C, Xin B, Zheng C, Zhao Y, Hao K, Wang Q, Wahl RL, Wang X and Zhou Y: 18F-FDG PET/CT radiomic analysis with machine learning for identifying bone marrow involvement in the patients with suspected relapsed acute leukemia. Theranostics. 9:4730–4739. 2019. View Article : Google Scholar : | |
Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, et al: Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 129:424–447. 2017. View Article : Google Scholar : | |
Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H and Thiele J: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. WHO Classification of Tumours; 2017 | |
Tallman MS, Wang ES, Altman JK, Appelbaum FR, Bhatt VR, Bixby D, Coutre SE, De Lima M, Fathi AT, Fiorella M, et al: Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 17:721–749. 2019. View Article : Google Scholar : PubMed/NCBI | |
Jondreville L, Krzisch D, Chapiro E and Nguyen-Khac F: The complex karyotype and chronic lymphocytic leukemia: prognostic value and diagnostic recommendations. Am J Hematol. 95:1361–1367. 2020. View Article : Google Scholar : PubMed/NCBI | |
Andreieva SV, Korets KV, Tsyapka OM and Skorokhod IM: Comparative Characteristics of Abnormal Karyotypes in Secondary Acute Leukemia. Cytol Genet. 58:292–299. 2024. View Article : Google Scholar | |
Olde Nordkamp L, Mellink C, van der Schoot E and van den Berg H: Karyotyping FISH, and PCR in acute lymphoblastic leukemia: competing or complementary diagnostics? J Pediatr Hematol Oncol. 31:930–935. 2009. View Article : Google Scholar : PubMed/NCBI | |
Camuset M, Le Calvez B, Theisen O, Godon C, Grain A, Thomas C, Couec ML, Béné MC, Rialland F and Eveillard M: Added value of molecular karyotype in childhood acute lymphoblastic leukemia. Cancer Innov. 2:513–523. 2023. View Article : Google Scholar : PubMed/NCBI | |
Kibler CE and Chabot-Richards DS: Molecular Pathology of Leukemia. Molecular Surgical Pathology. Cheng L, Netto GJ and Eble JN: Springer International Publishing; Cham: pp. 681–709. 2023, View Article : Google Scholar | |
Bayani J and Squire JA: Preparation of cytogenetic specimens from tissue samples. Curr Protoc Cell Biol. Chapter 22: Unit 22.2. 2004. View Article : Google Scholar | |
Stölzel F, Mohr B, Kramer M, Oelschlägel U, Bochtler T, Berdel WE, Kaufmann M, Baldus CD, Schäfer-Eckart K, Stuhlmann R, et al: Karyotype complexity and prognosis in acute myeloid leukemia. Blood Cancer J. 6:e3862016. View Article : Google Scholar : PubMed/NCBI | |
Kiefer Y, Schulte C, Tiemann M and Bullerdiek J: Chronic lymphocytic leukemia-associated chromosomal abnormalities and miRNA deregulation. Appl Clin Genet. 5:21–28. 2012.PubMed/NCBI | |
Alhourani E, Rincic M, Othman MA, Pohle B, Schlie C, Glaser A and Liehr T: Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH). Mol Cytogenet. 7:792014. View Article : Google Scholar : PubMed/NCBI | |
Han X, Jin C, Zheng G, Li Y, Wang Y, Zhang E, Zhu H and Cai Z: Acute myeloid leukemia with CPSF6-RARG fusion resembling acute promyelocytic leukemia with extramedullary infiltration. Ther Adv Hematol. 12:20406207209769842021. View Article : Google Scholar : PubMed/NCBI | |
Gupta V, Shariff M, Bajwa R, Patel I, Ayyad HA, Levitt MJ, Mencel PJ and Hossain MA: Acute myeloid leukemia acquiring promyelocytic leukemia-retinoic acid receptor alpha at relapse. World J Oncol. 10:153–156. 2019. View Article : Google Scholar : PubMed/NCBI | |
Hochhaus A, Baccarani M, Silver RT, Schiffer C, Apperley JF, Cervantes F, Clark RE, Cortes JE, Deininger MW, Guilhot F, et al: European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. Leukemia. 34:966–984. 2020. View Article : Google Scholar : PubMed/NCBI | |
Danylesko I, Jacoby E, Yerushalmi R, Shem-Tov N, Besser MJ, Vernitsky H, Marcu-Malina V, Shimoni A, Avigdor A and Nagler A: Remission of acute myeloid leukemia with t(8;21) following CD19 CAR T-cells. Leukemia. 34:1939–1942. 2020. View Article : Google Scholar : PubMed/NCBI | |
Bellesi S, Schiaffini G, Contegiacomo A, Maiolo E, Iacovelli C, Malafronte R, D'Innocenzo S, Alma E, Bellisario F, Viscovo M, et al: Enhancing lymphoma diagnosis on core needle biopsies: Integrating immunohistochemistry with flow cytometry. Cytometry B Clin Cytom. Jun 14–2024.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
Kurosawa S and Nakazato T: Immunohistochemical differentiation of extramedullary acute myeloid leukemia from blastic plasmacytoid dendritic cell neoplasm. Int J Hematol. 120:391–393. 2024. View Article : Google Scholar : PubMed/NCBI | |
Hisada Y, Archibald SJ, Bansal K, Chen Y, Dai C, Dwarampudi S, Balas N, Hageman L, Key NS, Bhatia S, et al: Biomarkers of bleeding and venous thromboembolism in patients with acute leukemia. J Thromb Haemost. 22:1984–1996. 2024. View Article : Google Scholar : PubMed/NCBI | |
De Coninck S, De Smedt R, Lintermans B, Reunes L, Kosasih HJ, Reekmans A, Brown LM, Van Roy N, Palhais B, Roels J, et al: Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma. Haematologica. 109:1373–1384. 2024. | |
Elliott MA and Tefferi A: Chronic neutrophilic leukemia: 2018 update on diagnosis, molecular genetics and management. Am J Hematol. 93:578–587. 2018. View Article : Google Scholar : PubMed/NCBI | |
Fiala GJ and Minguet S: Caveolin-1: The Unnoticed Player in TCR and BCR Signaling. Adv Immunol. 137:83–133. 2018. View Article : Google Scholar : PubMed/NCBI | |
Apostolopoulos A, Symeonidis A and Zoumbos N: Prognostic significance of immune function parameters in patients with chronic lymphocytic leukaemia. Eur J Haematol. 44:39–44. 1990. View Article : Google Scholar : PubMed/NCBI | |
Nardini G, Leopardi S and Bielli M: Clinical Hematology in Reptilian Species. Vet Clin North Am Exot Anim Pract. 16:1–30. 2013. View Article : Google Scholar : PubMed/NCBI | |
Oliveira ALCSL, Zerillo L, Cruz LJ, Schomann T, Chan AB, de Carvalho TG, Souza SVP, Araújo AA, de Geus-Oei LF and de Araújo Júnior RF: Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer. Mater Sci Eng C Mater Biol Appl. 120:1116782021. View Article : Google Scholar : PubMed/NCBI | |
Belov L, Huang P, Barber N, Mulligan SP and Christopherson RI: Identification of repertoires of surface antigens on leukemias using an antibody microarray. Proteomics. 3:2147–2154. 2003. View Article : Google Scholar : PubMed/NCBI | |
Hömig-Hölzel C and Savola S: Multiplex Ligation-dependent Probe Amplification (MLPA) in Tumor Diagnostics and Prognostics. Diagn Mol Pathol. 21:189–206. 2012. View Article : Google Scholar : PubMed/NCBI | |
Ningombam A, Verma D, Kumar R, Singh J, Ali MS, Pandey AK, Singh I, Bakhshi S, Sharma A, Pushpam D, et al: Prognostic relevance of NPM1, CEBPA, and FLT3 mutations in cytogenetically normal adult AML patients. Am J Blood Res. 13:28–43. 2023.PubMed/NCBI | |
Dietrich P, Gaza A, Wormser L, Fritz V, Hellerbrand C and Bosserhoff AK: Neuroblastoma RAS Viral Oncogene Homolog (NRAS) is a novel prognostic marker and contributes to sorafenib resistance in hepatocellular carcinoma. Neoplasia. 21:257–268. 2019. View Article : Google Scholar : PubMed/NCBI | |
Li S, Mason C and Melnick A: Genetic and epigenetic heterogeneity in acute myeloid leukemia. Curr Opin Genet Dev. 36:100–106. 2016. View Article : Google Scholar : PubMed/NCBI | |
Döhner H, Estey EH, Amadori S, Appelbaum FR, Büchner T, Burnett AK, Dombret H, Fenaux P, Grimwade D, Larson RA, et al: Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood. 115:453–474. 2010. View Article : Google Scholar | |
Menssen AJ and Walter MJ: Genetics of progression from MDS to secondary leukemia. Blood. 136:50–60. 2020. View Article : Google Scholar : PubMed/NCBI | |
Bond J, Touzart A, Leprêtre S, Graux C, Bargetzi M, Lhermitte L, Hypolite G, Leguay T, Hicheri Y, Guillerm G, et al: DNMT3A mutation is associated with increased age and adverse outcome in adult T-cell acute lymphoblastic leukemia. Haematologica. 104:1617–1625. 2019. View Article : Google Scholar : PubMed/NCBI | |
Stone RM: The difficult problem of acute myeloid leukemia in the older adult. CA Cancer J Clin. 52:363–371. 2002. View Article : Google Scholar : PubMed/NCBI | |
Appelbaum FR, Gundacker H, Head DR, Slovak ML, Willman CL, Godwin JE, Anderson JE and Petersdorf SH: Age and acute myeloid leukemia. Blood. 107:3481–3485. 2006. View Article : Google Scholar : PubMed/NCBI | |
Manescu P, Narayanan P, Bendkowski C, Elmi M, Claveau R, Pawar V, Brown BJ, Shaw M, Rao A and Fernandez-Reyes D: Detection of acute promyelocytic leukemia in peripheral blood and bone marrow with annotation-free deep learning. Sci Rep. 13:25622023. View Article : Google Scholar : PubMed/NCBI | |
Verma D, Yadav R, Ahirwar R and Meena P: Importance of bone marrow examination in cases of pancytopenia: A morphological study in a tertiary care center. Asian J Med Sci. 15:202–205. 2024. View Article : Google Scholar | |
Rivera D, Cui W, Gao J, Peker D, Zhang QY, Dewar R, Qiu L, Konoplev S, Hu Z, Sasaki K, et al: Aleukemic chronic myeloid leukemia without neutrophilia and thrombocytosis: A Report From the BCR::ABL1 Pathology Group. Mod Pathol. 37:1004062024. View Article : Google Scholar | |
Terwilliger T and Abdul-Hay M: Acute lymphoblastic leukemia: A comprehensive review and 2017 update. Blood Cancer J. 7:e5772017. View Article : Google Scholar : PubMed/NCBI | |
Jabbour E and Kantarjian H: Chronic myeloid leukemia: 2020 update on diagnosis, therapy and monitoring. Am J Hematol. 95:691–709. 2020. View Article : Google Scholar : PubMed/NCBI | |
Troussard X, Maître E and Cornet E: Hairy cell leukemia 2022: Update on diagnosis, risk-stratification, and treatment. Am J Hematol. 97:226–236. 2022. View Article : Google Scholar | |
Wood ME: Chapter 57-Oncologic Emergencies (Including Hypercalcemia). Critical Care Secrets (Fifth Edition). Parsons PE and Wiener-Kronish JP: Mosby; Philadelphia, PA: pp. 404–409. 2013, View Article : Google Scholar | |
Kang SH, Kim HK, Ham CK, Lee DS and Cho HI: Comparison of four hematology analyzers, CELL-DYN Sapphire, ADVIA 120, Coulter LH 750, and Sysmex XE-2100, in terms of clinical usefulness. Int J Lab Hematol. 30:480–486. 2008. View Article : Google Scholar : PubMed/NCBI | |
He G, Jiang Z, Xue S, Sun X and Wang W: Expression of LDH and CEA in serum in the process of targeted therapy of lung adenocarcinoma and the association between them and prognosis. Oncol Lett. 17:4550–4556. 2019.PubMed/NCBI | |
Oliveira LC, Romano LG, Prado-Junior BP, Covas DT, Rego EM and De Santis GC: Outcome of acute myeloid leukemia patients with hyperleukocytosis in Brazil. Med Oncol. 27:1254–1259. 2010. View Article : Google Scholar | |
Zografos E, Zagouri F, Kalapanida D, Zakopoulou R, Kyriazoglou A, Apostolidou K, Gazouli M and Dimopoulos MA: Prognostic role of microRNAs in breast cancer: A systematic review. Oncotarget. 10:7156–7178. 2019. View Article : Google Scholar | |
Davis-Dusenbery BN and Hata A: MicroRNA in Cancer: The Involvement of Aberrant MicroRNA Biogenesis Regulatory Pathways. Genes Cancer. 1:1100–1114. 2010. View Article : Google Scholar | |
Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, Frankel WL, Morgan DL, Postier RG, Brackett DJ and Schmittgen TD: Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer. 120:1046–1054. 2007. View Article : Google Scholar | |
Garzon R, Garofalo M, Martelli MP, Briesewitz R, Wang L, Fernandez-Cymering C, Volinia S, Liu CG, Schnittger S, Haferlach T, et al: Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin. Proc Natl Acad Sci USA. 105:3945–3950. 2008. View Article : Google Scholar : PubMed/NCBI | |
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, et al: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA. 99:15524–15529. 2002. View Article : Google Scholar | |
Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, Wang Y, Qian Z, Jin J, Zhang Y, et al: MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci USA. 104:19971–19976. 2007. View Article : Google Scholar : PubMed/NCBI | |
Marcucci G, Maharry K, Radmacher MD, Mrózek K, Vukosavljevic T, Paschka P, Whitman SP, Langer C, Baldus CD, Liu CG, et al: Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: A Cancer and Leukemia Group B Study. J Clin Oncol. 26:5078–5087. 2008. View Article : Google Scholar : PubMed/NCBI | |
Li Z, Lu J, Sun M, Mi S, Zhang H, Luo RT, Chen P, Wang Y, Yan M, Qian Z, et al: Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci USA. 105:15535–15540. 2008. View Article : Google Scholar : PubMed/NCBI | |
Abbott BL, Rubnitz JE, Tong X, Srivastava DK, Pui CH, Ribeiro RC and Razzouk BI: Clinical significance of central nervous system involvement at diagnosis of pediatric acute myeloid leukemia: A single institution's experience. Leukemia. 17:2090–2096. 2003. View Article : Google Scholar : PubMed/NCBI | |
Lin KI, Tam CS, Keating MJ, Wierda WG, O'Brien S, Lerner S, Coombes KR, Schlette E, Ferrajoli A, Barron LL, et al: Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens. Blood. 113:3168–3171. 2009. View Article : Google Scholar | |
Rai KR, Sawitsky A, Cronkite EP, Chanana AD, Levy RN and Pasternack BS: Clinical staging of chronic lymphocytic leukemia. Blood. 46:219–234. 1975. View Article : Google Scholar : PubMed/NCBI | |
Binet JL, Auquier A, Dighiero G, Chastang C, Piguet H, Goasguen J, Vaugier G, Potron G, Colona P, Oberling F, et al: A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer. 48:198–206. 1981. View Article : Google Scholar : PubMed/NCBI | |
Muñoz L, Lasa A, Carricondo MT, Hernández C, Ubeda J and Nomdedéu JF: Comparative analysis of ZAP-70 expression and Ig VH mutational status in B-cell chronic lymphocytic leukemia. Cytometry B Clin Cytom. 72:96–102. 2006.PubMed/NCBI | |
Michels E, Vandesompele J, De Preter K, Hoebeeck J, Vermeulen J, Schramm A, Molenaar JJ, Menten B, Marques B, Stallings RL, et al: ArrayCGH-based classification of neuroblastoma into genomic subgroups. Genes Chromosomes Cancer. 46:1098–1108. 2007. View Article : Google Scholar : PubMed/NCBI | |
Daver N, Schlenk RF, Russell NH and Levis MJ: Targeting FLT3 mutations in AML: Review of current knowledge and evidence. Leukemia. 33:299–312. 2019. View Article : Google Scholar : PubMed/NCBI | |
Sakaguchi M, Yamaguchi H, Najima Y, Usuki K, Ueki T, Oh I, Mori S, Kawata E, Uoshima N, Kobayashi Y, et al: Prognostic impact of low allelic ratio FLT3-ITD and NPM1 mutation in acute myeloid leukemia. Blood Adv. 2:2744–2754. 2018. View Article : Google Scholar : PubMed/NCBI | |
Kennedy VE and Smith CC: FLT3 mutations in acute myeloid leukemia: key concepts and emerging controversies. Front Oncol. 10:6128802020. View Article : Google Scholar | |
Basso G, Veltroni M, Valsecchi MG, Dworzak MN, Ratei R, Silvestri D, Benetello A, Buldini B, Maglia O, Masera G, et al: Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J Clin Oncol. 27:5168–5174. 2009. View Article : Google Scholar : PubMed/NCBI | |
Bader P, Kreyenberg H, Henze GH, Eckert C, Reising M, Willasch A, Barth A, Borkhardt A, Peters C, Handgretinger R, et al: Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: The ALL-REZ BFM Study Group. J Clin Oncol. 27:377–384. 2009. View Article : Google Scholar | |
Jongen-Lavrencic M, Grob T, Hanekamp D, Kavelaars FG, Al Hinai A, Zeilemaker A, Erpelinck-Verschueren CAJ, Gradowska PL, Meijer R, Cloos J, et al: Molecular Minimal Residual Disease in Acute Myeloid Leukemia. N Engl J Med. 378:1189–1199. 2018. View Article : Google Scholar : PubMed/NCBI | |
Vosberg S and Greif PA: Clonal evolution of acute myeloid leukemia from diagnosis to relapse. Genes Chromosomes Cancer. 58:839–849. 2019. View Article : Google Scholar : PubMed/NCBI | |
Lussana F, Caprioli C, Stefanoni P, Pavoni C, Spinelli O, Buklijas K, Michelato A, Borleri G, Algarotti A, Micò C, et al: Molecular detection of minimal residual disease before allogeneic stem cell transplantation predicts a high incidence of early relapse in adult patients with NPM1 positive acute myeloid leukemia. Cancers (Basel). 11:14552019. View Article : Google Scholar : PubMed/NCBI | |
Balatzenko G, Vundinti BR and Margarita G: Correlation between the type of bcr-abl transcripts and blood cell counts in chronic myeloid leukemia-a possible influence of mdr1 gene expression. Hematol Rep. 3:e32011. View Article : Google Scholar | |
Brinkmann U: Functional Polymorphisms of the Human Multidrug Resistance (MDR1) Gene: Correlation with P glycoprotein Expression and Activity in vivo. Novartis Found Symp. 243:207–10; discussion 207-212. 231-5. 2002. View Article : Google Scholar : PubMed/NCBI | |
Vendrik CP, Bergers JJ, De Jong WH and Steerenberg PA: Resistance to cytostatic drugs at the cellular level. Cancer Chemother Pharmacol. 29:413–429. 1992. View Article : Google Scholar : PubMed/NCBI | |
Vandyke K, Fitter S, Dewar AL, Hughes TP and Zannettino ACW: Dysregulation of bone remodeling by imatinib mesylate. Blood. 115:766–774. 2010. View Article : Google Scholar | |
Druker BJ, Guilhot F, O'Brien SG, Gathmann I, Kantarjian H, Gattermann N, Deininger MW, Silver RT, Goldman JM, Stone RM, et al: Five-Year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 355:2408–2417. 2006. View Article : Google Scholar : PubMed/NCBI | |
Millot F, Baruchel A, Guilhot J, Petit A, Leblanc T, Bertrand Y, Mazingue F, Lutz P, Vérité C, Berthou C, et al: Imatinib is effective in children with previously untreated chronic myelogenous leukemia in early chronic phase: Results of the French National Phase IV Trial. J Clin Oncol. 29:2827–2832. 2011. View Article : Google Scholar : PubMed/NCBI | |
Ebnöether M, Stentoft J, Ford J, Buhl L and Gratwohl A: Cerebral oedema as a possible complication of treatment with imatinib. Lancet. 359:1751–1752. 2002. View Article : Google Scholar : PubMed/NCBI | |
Mughal TI and Schrieber A: Principal long-term adverse effects of imatinib in patients with chronic myeloid leukemia in chronic phase. Biologics. 4:315–323. 2010. | |
Suttorp M and Millot F: Treatment of pediatric chronic myeloid leukemia in the year 2010: Use of tyrosine kinase inhibitors and stem-cell transplantation. Hematology Am Soc Hematol Educ Program. 2010:368–376. 2010. View Article : Google Scholar |